Best Practices For Adaptive Trial Designs Continue To Evolve
This article was originally published in Pharmaceutical Approvals Monthly
Data Monitoring Committees are one option to look at interim data and implement pre-planned adaptations to clinical trials, but the new duty could conflict with DMC’s safety responsibility, participants at a DIA conference note.
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A Drug Information Association working group survey found 477 studies between Jan. 1, 2008 and Sept. 1, 2011 utilized some type of adaptive design.