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BMS, Celldex combine cancer immunotherapies; BMS has negotiation rights to varlilumab

Executive Summary

In a Phase I/II trial that’s slated to begin in Q4 2014, Bristol-Myers Squibb Co. and Celldex Therapeutics Inc. (antibodies, antibody-drug conjugates, and vaccines that act as immunomodulators) agreed to study the safety, tolerability, and preliminary efficacy of a combination of their cancer immunotherapeutics--BMS’s PD-1 immune checkpoint inhibitor nivolumab with Celldex’s CD27 antagonist varlilumab--against multiple tumors, including non-small cell lung cancer, metastatic melanoma, ovarian, colorectal, and squamous cell head and neck.

Deal Industry
  • Pharmaceuticals
  • Biotechnology
    • Immuno-Oncology
    • Large Molecule
      • Antibodies
Deal Status
  • Final
Deal Type
  • Alliance
    • R&D and Marketing (Licensing)
    • Trial Collaborations

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