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Abbott files NDA for soft-gel capsule formulation of the protease inhibitor ritonavir. Manufacture of the original capsules was stopped because a new crystalline structure encountered during production affected the product's dissolution (1"The Pink Sheet" Aug. 3, 1998, p. 21). The product "was reformulated to accommodate a new and stable crystalline structure of ritonavir." Oral solution continues to be available in the interim
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