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Off-Label Promoter In Chief: President Trump Pushes COVID-19 Therapy

Executive Summary

If the President says over and over again that a drug is approved, does that make it so?

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Remdesivir EUA Includes Promotional Limitations Absent From Chloroquine Authorization

Printed materials and promotions must describe Gilead’s drug as authorized, not approved, for treating COVID-19; although similar boilerplate restrictions are part of most of the EUAs issued for diagnostics and equipment to combat the novel coronavirus, they were not included in the authorization for chloroquine/hydroxychloroquine. Remdesivir's new website strongly resembles an approved brand product site.

States Take Unusual Actions To Control On-Label Drug Supply Amidst COVID-19 Shortages

Sixteen US states have issued executive orders or other mandatory directives to preserve hydroxychloroquine and chloroquine for non-COVID-19 patients, while 26 states have issued similar voluntary guidance. The federal government is reserving some of the strategic national stockpile supply of the drugs for non-COVID-19, as private players in the supply chain also join in the efforts to balance on-label use with COVID-related demand. 

Supply Chain Truce In COVID-19: Will It Carry Over When Rx Price Debate Resumes?

Manufacturers, insurers, pharmacies and PBMs are united in trying to assure ongoing access to medicines amid the COVID-19 outbreak. Will making common cause in a national emergency mean a more cooperative approach to addressing US drug pricing concerns when normalcy returns?

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