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Ibuprofen, aspirin for platelet aggregation inhibition

This article was originally published in The Tan Sheet

Executive Summary

Taking 325 mg of aspirin followed by 400 mg of ibuprofen significantly reduces the magnitude and duration of inhibition of platelet aggregation, according to a study in the April Journal of Clinical Pharmacology. Researchers led by Francis M. Gengo, a pharmacy professor at State University of New York at Buffalo, conducted the study with 10 subjects taking either 325 mg of aspirin, 400 mg of aspirin or 400 mg of ibuprofen followed by 325 mg of aspirin two hours later. The researchers also conducted a confirmatory study for 27 months with 28 patients...

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