Reformulating pseudoephedrine products has posed a greater challenge than expected for a number of firms, as passage of a federal bill restricting sale of the ingredient looms

Sine-Off is the "first and only brand" of cough, cold, flu and sinus medicine to "completely remove pseudoephedrine from all of its products - not only nasal decongestants," Hogil Pharmaceutical announces Dec. 7. The line, which is now reformulated with phenylephrine, includes Sinus & Cold, Multi-Symptomand Sinus Painand iscurrently available in major mass retailers and drugstores nationwide. In addition, Hogil and its Sine-Off Charitable Foundation will provide an unrestricted educational grant to the Partnership for a Drug-Free America to support anti-meth measures, the firm announces. The firm will donate a percentage of sales from Sine-Off products to local anti-drug charities as well...

Compliance consultants warn that certain dietary supplement good manufacturing practices violations are inspection "showstoppers" and will draw agency enforcement