Vitamin E
This article was originally published in The Tan Sheet
Executive Summary
Three-year study finding "vitamin E supplement intake above 450 IU per day may block early atherosclerotic progression" pointed to by CRN to dispute contrary research in recent Journal of the American Medical Association article. Conducted by James Dwyer, PhD, University of Southern California, et al., and presented at a recent AHA conference, the CRN-cited study hypothesizes that other research on vitamin E and coronary heart disease may have failed to detect benefits due to insufficient dosing and intervention at later disease stages. Conversely, Emma Meagher, MD, University of Pennsylvania, et al., failed "to detect any impact of vitamin E on three quantitative indices of lipid peroxidation" in the March 7 JAMA study. Pennsylvania group's conclusions "were based on short-term markers of a biochemical process, not clinically significant disease markers" such as "the build-up of plaque in the arteries," CRN maintains