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Retinol vitamin A supplement high intake appears to increase birth defect risk -- NEJM.

This article was originally published in The Tan Sheet

Executive Summary

SUPPLEMENTARY RETINOL VITAMIN A AT OVER 10,000 IU LINKED TO BIRTH DEFECTS when taken by women prior to or at the outset of pregnancy, Boston University School of Medicine researchers reported in a paper to be published in the Nov. 23 New England Journal of Medicine. Kenneth Rothman, PhD, Boston University School of Medicine, et al. observed increased birth defects in babies born to women who consumed high amounts of vitamin A before the seventh week of gestation. Adverse events were not detected, however, at recommended vitamin A levels.

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