Ipilimumab Boosts Survival, But With Adverse Events That Need Strict Oversight
This article was originally published in The Pink Sheet Daily
Phase III results highlight need for management of immune-related side effects with vigilant monitoring and early steroid treatment.
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Decision to price combo of Yervoy and Opdivo at just 6% more than Yervoy monotherapy could set a trend for the market.
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Yervoy/Nivolumab May Need Stronger Survival Data To Be First Choice In Melanoma
Bristol’s combo demonstrates similar response rate as PD-1 alone, but with much better survival rates in a small melanoma study presented at ASCO. Due to toxicities, including one death, some say combination would need to shore up survival benefit to become first choice in frontline therapy.