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FDA Post-Marketing Clinical Trial Authority Should Be Bolstered, Topol Says

This article was originally published in The Pink Sheet Daily

Executive Summary

Cleveland Clinic researcher Topol's suggestion is part of a JAMA editorial critical of COX-2s following Pfizer's announcement that Celebrex demonstrated an increased cardiovascular risk in a cancer trial. Topol advocates for second-line use and a contraindication in high-risk patients.

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