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J&J Ultram "Dear Doctor" letter warns about drug abuse, seizure reports and anaphylactoid reactions.

Executive Summary

J&J ULTRAM "DEAR DOCTOR" LETTER ADVISES OF SEIZURES AND DRUG ABUSE reports received in the first year of marketing for the centrally acting analgesic. The letter was sent March 20 to over 900,000 physicians, physician assistants, nurse practitioners, pharmacists, podiatrists and dentists. Ultram is marketed by J&J subsidiary Ortho-McNeil and manufactured by R.W. Johnson.

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