Zeneca's Seroquel reduction in schizophrenia symptoms similar to haloperidol.
Executive Summary
ZENECA SEROQUEL SCHIZOPHRENIA SYMPTOM IMPROVEMENT SIMILAR TO HALOPERIDOL, according to results from Zeneca's North American Phase III trial of the antipsychotic agent reported at the American College of Neuropsychopharmacology annual meeting in Puerto Rico. Seroquel (ICI 204,636) 300 mg per day decreased symptoms as assessed by the Brief Psychiatric Rating Scale by 8.6 points compared to 7.6 points for haloperidol at the end of six weeks. The difference was not statistically significant.