Pink Sheet is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction
UsernamePublicRestriction

CELLTECH THREE THERAPEUTIC AGENTS IN PHASE I/II STUDIES

Executive Summary

CELLTECH THREE THERAPEUTIC AGENTS IN PHASE I/II STUDIES include: a tissue necrosis factor (TNF) product in Phase I and entering Phase II for septic shock; a calcitonin gene related peptide (CGRP), a vasodilator with potential applications in peripheral vascular diseases; and an undisclosed agent under development with another company. Celltech said it will also seek development and/or licensing partners for TNF and CGRP. The majority of Celltech's roughly $ 30 mil. in annual revenues (1988) are currently derived from its monoclonal antibody production business. Celltech has a number of contractual agreements with U.S. and overseas firms for development/production of antibodies, including a 1986 collaboration with American Cyanamid for the development of second generation monoclonal antibodies for cancer detection and treatment. Under terms of the original two year agreement, which was extended last year, American Cyanamid provided Celltech with $ 7.5 mil. in financing. Financial terms of the extended agreement have not been released. Among Celltech's other agreements are: a joint venture with Ortho for production of erythropoietin; a contract with Ortho Diagnostics for production of human anti-D monoclonal antibody; development of human growth hormone for Serono Labs; a licensing agreement with Sankyo for human calcitonin; and an agreement with an undisclosed partner in West Germany for development of human gastric lipase. The firm also has a $ 4.9 mil. contract from the National Institutes of Health, obtained in 1988, "to express genes for the AIDS antigens in its proprietary mammalian cell expression system and . . . raising monoclonal antibodies to the antigens," according to a company release. Approximately $ 5 mil. of Celltech's 1988 revenues were generated by its recently divested diagnostics business, Celltech Diagnostics to Novo BioLabs. The business had originally been a joint venture with Boots. Celltech projects that its 1989 revenues will be in the $ 30 mil. range.

You may also be interested in...



Part D Discount Liability Coming Into Focus: CMS Releases Drug Cost Data

Newly released Medicare Part D data sheds light on the sales hit that branded pharmaceutical manufacturers will face when the coverage gap discount program gets under way in 2011

FDA Skin Infections Guidance Spurs Debate On Endpoint Relevance

FDA appears headed for a showdown with clinicians and the pharmaceutical industry over the proposed new clinical trial endpoints for acute bacterial skin and skin structure infections, the guidance's approach for justifying a non-inferiority margin and proposed changes in the types of patients that should be enrolled in trials

Shire Hopes To Sow Future Deals With $50M Venture Fund

Specialty drug maker Shire has quietly begun scouting deals with a brand-new $50 million venture fund, the latest of several in-house investment arms to launch with their parent company's pipelines, not profits, as the measure of their worth

UsernamePublicRestriction

Register

LL009864

Ask The Analyst

Ask the Analyst is free for subscribers.  Submit your question and one of our analysts will be in touch.

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel