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Executive Summary

Licenses antihypertensive drug cicletanine, a furopyridine derivative, from French pharmaceutical company, Ipsen. Already registered in France, cicletanine has been found in studies to have a stimulatory effect on prostacyclin synthesis and to be similar in action to H1-antagonist mepyramine in blocking histamine-induced release of intracellular calcium ions and phosphoinositide metabolism....

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