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SK&F's TAGAMET IN BECTON-DICKINSON HYPAK PREFILLED SYRINGES

Executive Summary

SK&F's TAGAMET IN BECTON-DICKINSON HYPAK PREFILLED SYRINGES will be shipped to whslrs. beginning March 28, with hospital pharmacy availability expected by early April. The prefilled disposable syringes containing 300 mg/2 ml of Tagamet (cimetidine) will be whsle. priced at $34.60 for a box of 10. Approved by FDA March 2, the new dosage form is designed for intramuscular administration or use in intravenous admix programs for patients unable to take oral dosage forms. SK&F has utilized the Becton-Dickinson Hypak syringe system for its prefilled Compazine (prochlorperazine) for six years. Tagamet is currently approved for the treatment of duodenal ulcer, benign gastric ulcer and prevention of duodenal ulcer recurrence. Additional indications for the symptomatic relief of gastroesophageal reflux disease (GERD), twice-a-day dosing for duodenal ulcer treatment and the treatment of internal GI lesions in intensive care patients were recommended for approval by FDA's Gastrointestinal Drugs Advisory Cmte. in December.

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