Abbott Depakote ER epilepsy indication
This article was originally published in Pharmaceutical Approvals Monthly
Executive Summary
Abbott's Depakote ER (divalproex sodium extended-release) is approved Dec. 20 as once-daily monotherapy and adjunctive therapy for complex partial seizures in epileptic adults. Approval was based on two trials comparing once-daily Depakote ER to twice-daily and three times daily dosing of immediate-release Depakote