Coronavirus Notebook: EU Agencies Update On ‘Mix-And-Match’ & Booster Vaccines, UK Expands Human Challenge Trial

ExeVir’s potential antibody therapy against variants of concern is moving into clinical trials, and Irish researchers say an abandoned glioblastoma candidate compound could prevent respiratory and cardiovascular damage in COVID-19 patients.

Booster shot covid-19 vaccine concept
Regulators are looking into whether booster vaccines will be needed • Source: Alamy

There are “good grounds” to believe that “mix-and-match” COVID-19 vaccine regimes can be beneficial in terms of accelerating immunization programs and making the most of available vaccine supplies, but no clear guidance can yet be given on such a strategy, according to two key EU health agencies.

It is also too early to make recommendations on the usefulness of booster vaccines, although real-world data might prove useful...

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