Champagne Flows As CTLA-4/PD-1 Pioneers Allison And Honjo Win Nobel Prize

Joint prize for MD Anderson's James Allison and Kyoto University's Tasuku Honjo for checkpoint immunotherapy reflects decades of research and billions of IO dollars for industry.

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Inventor of the groundbreaking CTLA-4 checkpoint inhibitor Yervoy, James P. Allison, said he learned he had been awarded the Nobel Prize in Physiology or Medicine, along with PD-L1 pioneer Tasuko Honjo, through a call from his son at 5:30 a.m. on Oct. 1.

The Karolinska Institute's Nobel Assembly announced that day that James Allison, aged 70, of the MD Anderson Cancer Center in Houston, Texas, and Tasuko Honjo, aged 76 and a professor...

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