FDA Opens Door To Enhanced Applications For Quicker CMC Reviews

US FDA hopes to expedite NDA and ANDA reviews and lay groundwork for eventual ICH adoption by asking sponsors to make better use of CTD's Quality Overall Summary, which could allow agency reviewers to focus on patient impact and other key factors.

Quality Puzzle
Enhanced quality overall summaries could help FDA review applications faster • Source: FDA

The US FDA has invited pharmaceutical companies to explore new ways of using quality overall summaries to strengthen and expedite chemistry, manufacturing and control reviews of new and generic drugs.

What FDA and industry learn could help the International Conference on Harmonization as it considers updating the quality overall summary, a component of the Common Technical Document that ICH member...

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