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AstraZeneca pays $35mm up front for rights to Ardelyx's NH3 inhibitors; deal ends

Executive Summary

Ardelyx Inc. (developing therapeutics that target gut transporters and receptors related to cardiovascular, renal, and gastrointestinal diseases) has granted AstraZeneca PLC exclusive global rights to its sodium-hydrogen exchange 3 (NHE3) inhibitor program, including lead compound RDX5791, which is in Phase II trials for complications of end-stage renal disease (ESRD) and chronic kidney disease (CKD).
Deal Industry
  • Biotechnology
  • Pharmaceuticals
Deal Status
  • Terminated
Deal Type
  • Alliance
    • Co-Promotion
    • Includes Royalty or Profit Split Information
    • R&D and Marketing (Licensing)

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