In this month's issue of Start-Up, we profile Biolectrics, DigiSight Technologies, Redx Pharma and Woven Orthopedics.

One of the biggest challenges with orthopedic screws is inadequate fixation in poor quality bone; the revision rate of requiring a second surgery for loss of screw engagement is 15%. Woven Orthopedic Technologies LLC hopes to significantly reduce that rate with its braided polymer that is placed into a screw hole to provide good fixation within the entire bone.

One of the biggest challenges with orthopedic screws is inadequate fixation in poor quality bone; the revision rate of requiring a second surgery for loss of screw engagement is 15%. Woven Orthopedic Technologies LLC hopes to significantly reduce that rate with its braided polymer that is placed into a screw hole to provide good fixation within the entire bone.

Our 12th annual analysis reveals both an expansion of historical patterns of Series A financings and the emergence of a new group of heavily committed, relatively short-term investors.