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EASL Preview: Dual Versus Quad Combinations

This article was originally published in The Pink Sheet Daily

Executive Summary

Data on oral hepatitis C drugs from Pharmasset, Gilead, Vertex, Bristol-Myers and others will be watched closely at the EASL International Liver Congress.

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Pharmasset: A Breakout Year But Big Catalysts Lie Ahead

Although only half over, 2011 already has been pivotal for hepatitis C drug development, with the launch of two paradigm-shifting protease inhibitors, Johnson & Johnson/Vertex Pharmaceuticals Inc.'s Incivek (telaprevir) and Merck & Co.'s Victrelis (boceprevir). Both hit the market in May, even as attention is now shifting to the next big advance in HCV. Based on its work on next-gen HCV treatment, Pharmasset, Inc. has captivated the investment community.

Pharmasset: A Breakout Year But Big Catalysts Lie Ahead

Although only half over, 2011 already has been pivotal for hepatitis C drug development, with the launch of two paradigm-shifting protease inhibitors, Johnson & Johnson/Vertex Pharmaceuticals Inc.'s Incivek (telaprevir) and Merck & Co.'s Victrelis (boceprevir). Both hit the market in May, even as attention is now shifting to the next big advance in HCV. Based on its work on next-gen HCV treatment, Pharmasset, Inc. has captivated the investment community.

J&J's TMC435 Joins The Pharmasset Club

Pharmasset and J&J's Tibotec unit will initiate a Phase II study evaluating the combination of the investigational nucleotide polymerase inhibitor PSI-7977 and protease inhibitor TMC435.

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