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Novo Nordisk, Emisphere Collaborate To Propel Oral GLP-1 Compounds In R&D

This article was originally published in The Pink Sheet Daily

Executive Summary

Emisphere carrier technology may be applied to other compounds as well.

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Novo Signs Up Another Oral Insulin Partner, Hedging Its Bets

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Novo Signs Up Another Oral Insulin Partner, Hedging Its Bets

Novo Nordisk places another oral insulin technology bet with Emisphere; expands partnership with Merrion beyond insulin.

Can Oral GLP-1 Be More than Just Convenient?

Given the collapse of all the inhaled insulin collaborations, many observers are skeptical that the Novo/Emisphere collaboration to create an oral version of Novo's liraglutide GLP-1 -- the drug-delivery company's biggest deal ever -- will work out any better. GLP-1, however, doesn't have all the baggage of insulin therapy, so there is in fact better logic for an oral pill's success. Still, if the program creates merely an oral version of once-a-day liraglutide, with no clinical advantages over its GLP-1 competitors, it will die just as certainly as did inhaled insulin.

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