Pharmacia Eplerenone Use With Enalapril Enhances Efficacy, Firm Reports
This article was originally published in Pharmaceutical Approvals Monthly
Executive Summary
Pharmacia eplerenone combo use with enalapril shows improved efficacy over either agent alone in hypertensive patients with diabetic nephropathy or cardiac hypertrophy, according to study results presented by the company Nov. 21. Pharmacia is planning filings for the selective aldosterone blocker in first quarter 2002 for hypertension and in 2003 for heart failure. The firm is emphasizing the agent’s efficacy in combination use and in treatment of subpopulations, including African Americans and low-renin hypertensives