Opioid-Sparing Claims May Be Better Suited For Phase IV Trials Instead Of Phase III
Executive Summary
US FDA advisory committee panelists argue that prospective, randomized Phase III trials fail to reflect real-world treatment decisions.
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Xpovio Clinical Development Timeline
Chronicle of the development and review of Karyopharm's Xpovio (selinexor) for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least four prior therapies.