Listerine line extension zeroes out alcohol: Johnson & Johnson formulates its Listerine Zero mouthwash with four essential oils but no alcohol. The product claims to kill germs and freshen breath with a formula less intense than other antiseptics. Listerine Zero, in Clean Mint flavor, launched Aug. 4 across food, drug and mass merchandise outlets, in four stock-keeping units ranging from 250 mL to 1.5 L. Suggested retail prices are from $3.89 to $8.49, J&J says

FDA has raised questions on "minor" issues regarding SCOLR Pharma's proposed nonprescription 12-hour pseudoephedrine tablet, according to the firm

While it was not as affected as some other countries, Japan still had the pandemic to deal with and regulators responded while managing to keep up regular product review work, including several world-first approvals. Coronavirus vaccine roll-outs and the first general annual reimbursement price cut are on the cards for this year.