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Study Suggests Aspirin Use Enhances Survival After Breast Cancer

This article was originally published in The Tan Sheet

Executive Summary

Aspirin use after the diagnosis of stage I to III breast cancer was associated with a decreased risk of breast cancer death and distant recurrence - when cancer has metastasized to another part of the body - according to results from the ongoing Nurses' Health Study

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Regular aspirin use may lower the risk of cancer-specific mortality among patients diagnosed with nonmetastatic colorectal cancer, according to a Journal of the American Medical Association study. Of the 840 women and 439 men participating in the Nurses' Health Study and the Health Professionals Follow-Up Study, 222 died from colorectal cancer. Only 15 percent of these deaths occurred among regular aspirin users, whereas 19 percent of deaths occurred among subjects who did not regularly use aspirin after their diagnosis, according to lead researcher Andrew Chan of Massachusetts General Hospital and Harvard Medical School and his associates. The results suggest this cancer type is sensitive to aspirin's potential anticancer effect, though cyclo-oxygenase-2-negative tumors might be aspirin-resistant

Research & Development In Brief

Coffee reduces ovarian cancer: Caffeine may reduce the risk of ovarian cancer, particularly in women who do not use hormones, according to the March 1 journal CANCER, which revealed findings of Shelley S. Tworoger, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, et al. "The potential reduction in risk with higher caffeine intake appeared to be strongest for women who had never used oral contraceptives or postmenopausal hormones," an abstract of the study notes. Researchers also found cigarette smoking may only increase the risk for mucinous ovarian tumors, and alcohol intake is not associated with risk. Researchers gleaned data from questionnaires from the Nurses' Health Study, examining associations between caffeine or alcohol and ovarian cancer risk among 80,253 women between 1976 and 2004. Tworoger, et al. claim more research is needed...

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A high-dose, purified form of an omega-3 fatty acid shrunk colorectal polyps about as effectively as the non-steroidal anti-inflammatory drug commonly used to treat them, but without the associated cardiovascular risks, according to findings from a trial published in the journal Gut

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