Pink Sheet is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction
UsernamePublicRestriction

NSAIDs vs. Tylenol

This article was originally published in The Tan Sheet

Executive Summary

Non-steroidal anti-inflammatory drugs are superior to acetaminophen for improving knee and hip pain in people with osteoarthritis, a review published in The Cochrane Database of Systematic Reviews finds. Tanveer Towheed, MD, Queen's University, Ontario, et al., analyzed 15 randomized controlled trials gleaned from a search of databases including MEDLINE and EMBASE; the studies dated from 1994 to July 2005 and lasted an average of six weeks. Researchers reviewed data on almost 6,000 people with osteoarthritis who took 4,000 mg of acetaminophen (McNeil's Tylenol) per day with those who took placebo or NSAID. Subjects who took NSAIDs reported lower levels of pain and increased movement; "in osteoarthritis subjects with moderate-to-severe levels of pain, NSAIDs appear to be more effective than acetaminophen," Towheed et al. state...

You may also be interested in...



QUOTED. 19 February 2020. Stephen Hahn.

The US FDA has abandoned all near-term plans to inspect Chinese manufacturing facilities in the wake of the coronavirus crisis. See what agency head Stephen Hahn said about it here.

DevaCurl Faces Multiple Class Actions As Latest Brand Linked To Hair Loss

The company maintains that its products are safe, but plaintiffs in proposed class actions allege it has knowingly put consumers at risk of hair loss and other injuries. DevaCurl’s troubles escalated quickly after a former brand ambassador went viral with a 31 January video urging consumers to stop using DevaCurl products and adopt safer alternatives.

Could ICER Outreach To US FDA Lead To Better Cost Effectiveness Analyses?

To aid its value assessments, ICER is interested in helping FDA understand the importance of patient-relevant outcomes and consistent endpoints across trials of drugs for the same disease.

Topics

UsernamePublicRestriction

Register

PS099073

Ask The Analyst

Please Note: You can also Click below Link for Ask the Analyst
Ask The Analyst

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel