NSAIDs and oral cancer
This article was originally published in The Tan Sheet
Executive Summary
Long-term use of NSAIDs was linked to reduced incidence of oral cancer, but also was associated with increased risk of death from cardiovascular disease, an online study published Oct. 7 by The Lancet finds. The nested case-control study analyzed data from the Norwegian Health Survey database and identified individuals with oral cancer out of the 9,241 participants who had an increased risk for oral cancer due to heavy smoking, Jon Sudbø, MD, Norwegian Radium Hospital, Oslo, Norway, et al., state. Matched controls were chosen from the heavy smokers who did not have cancer. "NSAID use for 15 or more years had the lowest and most highly significant hazard ratio [.30] for oral cancer," Sudbø et al. explain. However, the finding linking increases in death due to cardiovascular disease and long-term NSAID use "highlights the need for a careful risk-benefit analysis when the long-term use of NSAIDs is considered," the authors say...
You may also be interested in...
Pink Sheet Podcast: Woodcock To Be Acting US FDA Chief, Key Staff Depart, Political Donations Shift
Pink Sheet reporters and editor discuss President-Elect Joe Biden’s decision to name the CDER director as acting FDA commissioner and other staffing changes, as well as changes to industry trade groups’ political donations.
Liquid Biopsy Company Delfi Diagnostics Raised $100M For New Class of Early Cancer Detection Test
Delfi Diagnostics will use the new funds to expand its team of cancer researchers and machine-learning experts to validate its novel approach for early cancer detection through multiple prospective clinical trials.
Biotin And ‘Healthy Hair’: Federal Pre-emption Clips False Advertising Complaint In California
US Ninth Circuit affirms a district court’s summary judgment in favor of Target and manufacturer of Up & Up brand biotin supplement it sells. Indian manufacturer targeted in putative class-action in New York prompted FDA’s 2016 creation of import alert category for Ayurvedic supplements.
Need a specific report? 1000+ reports available
Buy Reports
Register for our free email digests: