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Ephedra-related psychiatric events?

This article was originally published in The Tan Sheet

Executive Summary

The majority of the 1,820 ephedra-related adverse event reports submitted to FDA "were insufficiently documented to make an informed judgment about a relationship between ephedra use and the event," Margaret Maglione, RAND Corporation, et al., report in the January American Journal of Psychiatry. Independent reviews by a psychologist and psychiatrist indicated 57 "serious" psychiatric events, two-thirds of which involved patients who had "preexisting psychological conditions and/or use of other mood-altering medications or illicit substances." The serious events included, but were not limited to psychosis, mania, severe depression, delusions and hallucinations. Researchers point to the "rapid resolution of psychiatric symptoms" following the end of ephedra use as support for the botanical's role in the events. Still, they suggest clinicians remain aware of a link between serious psychiatric symptoms and ephedra...
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