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Folic acid research

This article was originally published in The Tan Sheet

Executive Summary

Low- and moderate-dose folic acid and multivitamin supplements "do not improve brachial artery flow-mediated vasodilation [FMD] in older adults with mild hyperhomocysteinemia," study published in the September American Heart Journal concludes. The prospective, single-blinded study followed 27 subjects age 70 and older with the condition for 40 weeks. Participants took placebo for 10 weeks, a daily multivitamin for 10 weeks, placebo for 10 weeks and a multivitamin supplement and folic acid supplement for 10 weeks. During the study, homocysteine levels decreased, but FMD "did not change significantly," Cynthia Carlsson, MD, University of Wisconsin, et al., conclude. FMD "did not improve after therapy with multivitamin alone," the authors add...
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