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NSAIDs and heart failure

This article was originally published in The Tan Sheet

Executive Summary

Patients with history of congestive heart failure have increased risk of repeat CHF when using NSAIDs, Johan Feenstra, MD/PhD, Erasmus Medical Center, Rotterdam, The Netherlands, et al., report in Feb. 11 Archives of Internal Medicine. Trial involved 7,277 participants in the Rotterdam Study; subjects were followed until diagnosis of incident heart failure, death, removal from the study area or end of the roughly seven-year follow-up period. Researchers documented 345 incidents of heart failure, found subjects who had filled at least one NSAID prescription since diagnosis with CHF were 9.9 times more likely to relapse than those who did not. However, Feenstra et al. note use of NSAIDs is not associated with an increased risk for an initial case of heart failure...
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