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NSAIDs & ulcers

This article was originally published in The Tan Sheet

Executive Summary

Peptic ulcers are "significantly more common in H. pylori infected NSAID takers than in takers without the infection, suggesting a possible interaction," Canadian researchers report in Jan. 5 Lancet. In a meta-analysis, Jia-Qing Huang, et al., McMaster University Medical Center, identified 16 studies with data on H. pylori status for 1,625 NSAID users. "In five controlled studies, peptic ulcer disease was significantly more common in NSAID takers (35.8%) than in controls (8.3%) irrespective of H. pylori infection. Compared with H. pylori negative individuals not taking NSAIDs, the risk of ulcer in H. pylori infected NSAID takers was 61.1," researchers say...
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