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Creatine review

This article was originally published in The Tan Sheet

Executive Summary

Evidence showing creatine increases muscle mass, strength, endurance and recovery time is "limited at best" and "large-scale, well-controlled studies must show the positive effects of creatine supplementation before pharmacists can recommend it," Angie Graham and Randy Hatton conclude in a review of creatine research published in the November/December issue of the Journal of the American Pharmaceutical Association. Human studies were collected from MEDLINE, Current Contents, BIOSIS, Science Citation Index and the popular media. The authors report conclusive data on short- and long-term safety as well as drug interactions do not exist. Moreover, product impurities could lead to "unexpected adverse events," they state
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