Pink Sheet is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction
UsernamePublicRestriction

Ketoprofen/acetaminophen GI effects

This article was originally published in The Tan Sheet

Executive Summary

Seven-day study involving 24 healthy subjects finds "even at lower (OTC) doses (75 mg/day) ketoprofen is associated with significant gastrointestinal irritation," researchers from Houston Institute of Clinical Research and McNeil Consumer Products (Tylenol) report. Published in the July American Journal of Gastroenterology, the randomized, double-blind, three-way crossover study compared ketoprofen with acetaminophen 4,000 mg/day. "The acetaminophen group showed no difference from placebo," while two subjects on ketoprofen developed "frank gastric ulcers," Frank Lanza, MD, et al. note. The Aspirin Foundation of America said the study is "obviously biased and...dangerously misleading." Bayer (Actron) and Whitehall-Robins (Orudis KT) sell OTC ketoprofen products...
Advertisement
Advertisement

Topics

Advertisement
UsernamePublicRestriction

Register

PS088695

Ask The Analyst

Please Note: You can also Click below Link for Ask the Analyst
Ask The Analyst

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel