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Phenolphthalein linked to greater lymphoma incidence at high doses in mice -- NTP.

This article was originally published in The Tan Sheet

Executive Summary

PHENOLPHTHALEIN LINKED TO GREATER LYMPHOMA INCIDENCE IN TRANSGENIC MICE at high doses in new data presented April 30 by the National Toxicology Program/National Institute of Environmental Health Sciences to FDA's Carcinogenicity Assessment Committee at a meeting in Rockville, Md. After hearing the presentation on phenolphthalein, FDA's in-house cancer study review board voted in closed session on a number of questions regarding the safety of phenolphthalein. Following tabulation of the vote, the committee will provide recommendations to FDA's OTC division about the laxative ingredient.
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