Pink Sheet is part of the Business Intelligence Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction
UsernamePublicRestriction

Traveler's diarrhea

This article was originally published in The Tan Sheet

Executive Summary

Review article in the June 24 issue of the New England Journal of Medicine recommends use of bismuth subsalicylate "if after careful counseling parents still wish a child to use a prophylactic drug" for traveler's diarrhea. For adult prophylaxis, Herbert Dupont, MD, and Charles Ericsson, MD, University of Texas Medical School, recommended antibacterial drugs as well as lactobacillus preparations and bismuth subsalicylate, which, they note, has "few side effects." For symptomatic treatment, the authors note that "antibacterial drugs are more effective in curing intestinal infection, but their onset of action is slower than that of bismuch subsalicylate or loperamide." FDA rejected P&G's request for a traveler's diarrhea indication for its bismuch subsalicylate product Pepto Bismol in April 1992 citing insufficient data. McNeil's loperamide product Imodium A-D was approved for that indication in November 1992 ("The Tan Sheet" March 1, In Brief)...
Advertisement

Topics

Advertisement
UsernamePublicRestriction

Register

PS081621

Ask The Analyst

Please Note: You can also Click below Link for Ask the Analyst
Ask The Analyst

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel