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Repurposing Leptin: How a “Fat Drug” Became a Model for a Leaner Industry

This article was originally published in RPM Report

Executive Summary

Two decades ago, the “fat dissolving” protein leptin was touted as one of the biggest opportunities in biotech—based on preclinical rodent studies. The compound may finally be making it to market in a very different model: as an orphan drug sponsored by Big Pharma.

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