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Yervoy/Zelboraf Combo Trial Fails, But Sequential Study Continues

This article was originally published in The Pink Sheet Daily

Executive Summary

Small Phase I melanoma study testing a combination of Zelboraf and Yervoy was closed early due to an unexpectedly high rate of liver toxicity, investigators report in letter to the editor of the New England Journal of Medicine. A sequential study of Yervoy and Zelboraf and other combination studies proceed as planned.

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