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GSK Announces Share Buyback Program As Pretax Profits Fall By 52% In 2010

This article was originally published in The Pink Sheet Daily

Executive Summary

GlaxoSmithKline plans to divest non-core OTC brands this year as CEO describes 2010 as a challenging year.

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Uncertain Future For Otelixizumab In Type 1 Diabetes After Phase III Failure

Phase III disappointment for GSK/Tolerx-partnered drug follows last fall's Phase III miss by Lilly and MacroGenics' anti-CD3 antibody in same indication.

Uncertain Future For Otelixizumab In Type 1 Diabetes After Phase III Failure

Phase III disappointment for GSK/Tolerx-partnered drug follows last fall's Phase III miss by Lilly and MacroGenics' anti-CD3 antibody in same indication.

Uncertain Future For Otelixizumab In Type 1 Diabetes After Phase III Failure

GlaxoSmithKline and Tolerx announced March 11 that their humanized anti-CD3 monoclonal antibody, otelixizumab failed to meet the primary endpoint in the Phase III DEFEND-1 trial for type 1 diabetes, and they were halting recruitment and dosing in another Phase III trial, DEFEND-2, while they review the DEFEND-1 results.

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