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Vertex Braces For HCV Combo Paradigm With ViroChem Buyout

This article was originally published in The Pink Sheet Daily

Executive Summary

Takeover gives Vertex two clinical-stage polymerase inhibitors, and recalls Gilead’s key Triangle grab.

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Drop Two, Add One: Vertex Adjusts Adaptive Trial Seeking An All-Oral HCV Regimen

Vertex Pharmaceuticals, Inc., is adjusting an ongoing trial that tests its potential first-in-class protease inhibitor telaprevir in combinations it hopes will lead to an all-oral cocktail that is effective against genotype 1 hepatitis C, the firm announced Dec. 21.

Drop Two, Add One: Vertex Adjusts Adaptive Trial Seeking An All-Oral HCV Regimen

Vertex Pharmaceuticals, Inc., is adjusting an ongoing trial that tests its potential first-in-class protease inhibitor telaprevir in combinations it hopes will lead to an all-oral cocktail that is effective against genotype 1 hepatitis C, the firm announced Dec. 21.

Drop Two, Add One: Vertex Adjusts Adaptive Trial Seeking An All-Oral HCV Regimen

The ongoing Phase II study trying combinations backboned by telaprevir and experimental polymerase inhibitor VX-222 continues with two quad-treatment arms and a plan to drop interferon again in the first quarter.

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