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Organon Asenapine Study Shows Improved Effect On Negative Schizophrenia Symptoms Over Risperdal

This article was originally published in The Pink Sheet Daily

Executive Summary

Patients treated with asenapine also experienced less weight gain and lower levels of prolactin, a signal associated with improved sexual side effects.

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Schering’s acquisition of asenapine developer Organon was completed Nov. 19; Dutch firm has previously reported positive data in comparison to J&J’s Risperdal and Lilly’s Zyprexa.

FDA Accepts NDA For Schering-Plough Antipsychotic Asenapine

Schering’s acquisition of asenapine developer Organon was completed Nov. 19; Dutch firm has previously reported positive data in comparison to J&J’s Risperdal and Lilly’s Zyprexa.

Organon’s Asenapine Shows Less Weight Gain Than Zyprexa In Phase III Trial

Patients taking asenapine had approximately two-fold lower incidence of clinically significant weight gain; efficacy profile was similar to Lilly’s olanzapine.

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