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Natrecor Safety Confirmed In ADHERE Heart Failure Registry, J&J Says

This article was originally published in The Pink Sheet Daily

Executive Summary

Johnson & Johnson defends safety of nesiritide, says hospital registry shows Natrecor is associated with significantly lower mortality rate than milrinone or dobutamine, and a rate equivalent to that of nitroglycerin.

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J&J Natrecor "Dear Doctor" Letter Discusses Appropriate Use In Heart Failure

Scios uses "Dear Doctor" letter to alert physicians to independent panel's recommendations for appropriate and inappropriate uses of nesiritide. The letter recommends use of Natrecor only in a clinical setting where blood pressure can be closely monitored.

J&J Natrecor "Dear Doctor" Letter Discusses Appropriate Use In Heart Failure

Scios uses "Dear Doctor" letter to alert physicians to independent panel's recommendations for appropriate and inappropriate uses of nesiritide. The letter recommends use of Natrecor only in a clinical setting where blood pressure can be closely monitored.

Natrecor Use Should Be Limited, Independent Panel Convened By J&J Says

The cardiologist panel calls for use of the congestive heart failure therapy to be "strictly limited" to patients that present with symptoms in the hospital setting. The expert panel also recommends that Scios "immediately undertake" a professional educational campaign about Natrecor's appropriate uses.

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