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Pfizer's Celebrex, Bextra Targets Of Public Citizen Withdrawal Petition

This article was originally published in The Pink Sheet Daily

Executive Summary

Public Citizen tells FDA that COX-2 inhibitors have inherent cardiovascular risks and offer no efficacy advantages over non-selective NSAIDs. The group suggests the mechanism that creates the COX-2 inhibitors' thrombogenicity is "increased platelet-vessel wall interactions and firm adhesions."

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