Threshold Presses On In Two Phase III Cancer Trials As Competitors Wilt
Threshold and partner Merck Serono are benefiting from recent high-profile failures in sarcoma and pancreatic cancer. Armed with $100 million in payments since signing with Merck in February 2012, Threshold needs to rise above stiff odds and what some view as equivocal Phase II pancreatic cancer results.
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Threshold Pharmaceuticals’ lead compound from its hypoxia-activated prodrug platform, TH-302, is partnered with Merck KGaA on one Phase III program and in internal development for another Phase III.
Having emerged from a radical restructuring with new senior management, a revamped portfolio and a strategic ambition to morph into an oncology powerhouse on the back of its emerging markets business, CEO Belén Garijo says Merck Serono is poised to enter its growth phase.
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