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Bad News/Good News For Cholesterol: Another Strike Against HDL, But Support For Stricter LDL Targets

Executive Summary

A large genetic analysis published in the Lancet suggests that drugs that raise HDL may not reduce cardiovascular risk, creating more bad news for a field still reeling from the failure of Roche’s dalcetrapib. But another study calls for much wider use of LDL-lowering drugs, even in patients with low cardiovascular risk.

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