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Provenge Nod Lifts Spirits And Stocks, But Also Sets High Bar For Success

Executive Summary

Approval of Dendreon's Provenge is a major achievement and a shot in the arm for the growing field of therapeutic cancer vaccines, but it also serves as a reminder of the high bar for clinical and regulatory success in uncharted territory

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Hopes For Glaxo’s MAGE-A3 Vaccine Grow Dim As Trial Misses Endpoint

Glaxo’s vaccine fails co-primary endpoint in Phase III DERMA study of melanoma – trial is allowed to continue but hopes for success are not high. Top-line release raises specter that drug could become yet another failed cancer vaccine.

Efficacy Signal For Lilly’s Solanezumab Stirs The Alzheimer’s Pot

With the potential for a multi-billion-dollar blockbuster on its hands, Eli Lilly could conduct a confirmatory trial or even seek near-term approval of sola after pooled data revealed a hint of disease modifying potential in mildly affected Alzheimer’s patients, though the company also may be grasping at straws.

With IPO Off The Table, Argos Takes $25 Million From VCs

The cancer immunotherapy developer withdrew its IPO registration last month, turning instead to insider investors as it prepares for a pivotal Phase III trial on a dendritic cell treatment.

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