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Aetna Plans “Clinical Alert” On Plavix Use With PPIs Based On Claims Review

Executive Summary

Aetna is developing a clinical alert for physicians and pharmacists to warn about potentially reduced effectiveness for Plavix (clopidogrel) when the antiplatelet drug is used concurrently with a proton pump inhibitor, such as Prilosec (omeprazole) or Nexium (esomeprazole)

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