Ortho-McNeil's anti-convulsant Topamax (topiramate) clears FDA Aug. 11 for supplemental indication of prophylaxis of migraine headaches in adults. The recommended daily dose for migraines is 100 mg administered in two divided doses. Topamax' twice-daily migraine prevention regimen may place the drug at a disadvantage to Abbott's Depakote ER (divalproex extended-release), which has once-daily dosing . Ortho-McNeil received an "approvable" letter for the migraine indication in October 2003 (1"The Pink Sheet" Nov. 24, 2003, In Brief)...

Physicians should periodically examine Topamax (topiramate) patients for metabolic acidosis, a Johnson & Johnson "Dear Health Care Professional" letter recommends

Despite AI and digital analytics playing an increasing role in pharma, the industry lags others globally, a recent event heard. Meanwhile, top Indian players including Sun Pharma, Cipla and others shared what is driving their initiatives, ranging from a 'touchless factory' to virtual training and lessons learned along the way.