Pharmacia Zyvox

Submission to FDA of cases of suspected vancomycin-resistant Enterococcus faecium resistant to linezolid will likely show a lower frequency of documented cases of resistance than reported in an April 14 article in The Lancet. In the 45-patient study, one patient (2.2%) had documented resistance to linezolid in VRE. Pharmacia's reports to FDA will include patients from clinical trials and compassionate-use programs. The company intends to file for the treatment of infections due to penicillin-resistant Streptococcus pneumoniae at the end of 2001 or early 2002